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Bortezomib Induces Apoptosis of Epstein-Barr Virus (EBV)-Transformed B Cells and Prolongs Survival of Mice Inoculated with EBV-Transformed B Cells

Bortezomib, an inhibitor of the 26S proteasome, is currently approved for treatment of multiple myeloma and is being studied for therapy of non-Hodgkin's lymphoma. We found that Epstein-Barr virus (EBV)-positive B cells with type III latency were more susceptible to killing by bortezomib than t...

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Detalhes bibliográficos
Main Authors: Zou, Ping, Kawada, Junichi, Pesnicak, Lesley, Cohen, Jeffrey I.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2045383/
https://ncbi.nlm.nih.gov/pubmed/17626072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02241-06
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