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The Amino Acid Residues at Positions 120 to 123 Are Crucial for the Antigenicity of Hepatitis B Surface Antigen

The major hydrophilic region (MHR) of hepatitis B surface antigen (HBsAg) harbors conformational B-cell epitopes and is the major target of neutralizing antibodies to HBsAg (anti-HBs). Mutant HBsAg (mtHBsAg) with amino acid substitutions such as G145R is known to affect the binding of specific anti-...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Tian, Yongjun, Xu, Yang, Zhang, Zhenhua, Meng, Zhongji, Qin, Li, Lu, Mengji, Yang, Dongliang
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2007
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2045265/
https://ncbi.nlm.nih.gov/pubmed/17609325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.00508-07
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