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Mutational Analysis of Active Site Residues Essential for Sensing of Organic Hydroperoxides by Bacillus subtilis OhrR

Bacillus subtilis OhrR is the prototype for the one-Cys family of organic peroxide-sensing regulatory proteins. Mutational analyses indicate that the high sensitivity of the active site cysteine (C15) to peroxidation requires three Tyr residues. Y29 and Y40 from the opposing subunit of the functiona...

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Detalhes bibliográficos
Main Authors: Soonsanga, Sumarin, Fuangthong, Mayuree, Helmann, John D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2045209/
https://ncbi.nlm.nih.gov/pubmed/17660290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00879-07
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