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Oxidation of a single active site suffices for the functional inactivation of the dimeric Bacillus subtilis OhrR repressor in vitro

Bacillus subtilis OhrR is a dimeric repressor that senses organic peroxides and regulates the expression of the OhrA peroxiredoxin. Derepression results from oxidation of an active site cysteine which ultimately results in formation of a mixed disulfide with a low molecular weight thiol, a cyclic su...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Eiamphungporn, Warawan, Soonsanga, Sumarin, Lee, Jin-Won, Helmann, John D.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2009
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2651793/
https://ncbi.nlm.nih.gov/pubmed/19129220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn1052
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