An integrative in silico approach for discovering candidates for drug-targetable protein-protein interactions in interactome data

BACKGROUND: Protein-protein interactions (PPIs) are challenging but attractive targets for small chemical drugs. Whole PPIs, called the 'interactome', have been emerged in several organisms, including human, based on the recent development of high-throughput screening (HTS) technologies. I...

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Detalhes bibliográficos
Main Authors: Sugaya, Nobuyoshi, Ikeda, Kazuyoshi, Tashiro, Toshiyuki, Takeda, Shizu, Otomo, Jun, Ishida, Yoshiko, Shiratori, Akiko, Toyoda, Atsushi, Noguchi, Hideki, Takeda, Tadayuki, Kuhara, Satoru, Sakaki, Yoshiyuki, Iwayanagi, Takao
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2045083/
https://ncbi.nlm.nih.gov/pubmed/17705877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2210-7-10
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