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Assessing the druggability of protein-protein interactions by a supervised machine-learning method

BACKGROUND: Protein-protein interactions (PPIs) are challenging but attractive targets of small molecule drugs for therapeutic interventions of human diseases. In this era of rapid accumulation of PPI data, there is great need for a methodology that can efficiently select drug target PPIs by holisti...

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Detalhes bibliográficos
Main Authors: Sugaya, Nobuyoshi, Ikeda, Kazuyoshi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2739204/
https://ncbi.nlm.nih.gov/pubmed/19703312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-10-263
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