Structure and Function of a Potent Agonist for the Semi-Invariant NKT Cell Receptor

NKT cells express a conserved, semi-invariant αβ T cell receptor, which has specificity for a self-glycosphingolipids and microbial cell wall α-glycuronosylceramide antigens presented by CD1d molecules. Here we report the crystal structure of CD1d in complex with a short-chain synthetic variant of α...

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Main Authors: Zajonc, Dirk M., Cantu, Carlos, Mattner, Jochen, Zhou, Dapeng, Savage, Paul B., Bendelac, Albert, Wilson, Ian A., Teyton, Luc
Formato: Artigo
Idioma:Inglês
Publicado: 2005
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2045075/
https://ncbi.nlm.nih.gov/pubmed/16007091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni1224
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