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The effect of indomethacin on the contractile response of the guinea-pig lung parenchymal strip to leukotrienes B4, C4, D4 and E4.

Indomethacin (1 microgram ml-1) almost totally inhibited the dose-dependent contractile response of isolated lung parenchymal strips of the guinea-pig (GPLS) to leukotriene B4 (LTB4) over the concentration range 0.18-18 nM. LTC4 (0.63 pM-63 nM)-induced contractions of GPLS were not significantly inh...

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Detalhes bibliográficos
Main Authors: Austen, K. F., Corey, E. J., Drazen, J. M., Leitch, A. G.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1983
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2044975/
https://ncbi.nlm.nih.gov/pubmed/6652374
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