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High-resolution structure of the E.coli RecQ helicase catalytic core

RecQ family helicases catalyze critical genome maintenance reactions in bacterial and eukaryotic cells, playing key roles in several DNA metabolic processes. Mutations in recQ genes are linked to genome instability and human disease. To define the physical basis of RecQ enzyme function, we have dete...

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Bibliografiske detaljer
Main Authors: Bernstein, Douglas A., Zittel, Morgan C., Keck, James L.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC204483/
https://ncbi.nlm.nih.gov/pubmed/14517231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg500
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