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High-resolution structure of the E.coli RecQ helicase catalytic core

RecQ family helicases catalyze critical genome maintenance reactions in bacterial and eukaryotic cells, playing key roles in several DNA metabolic processes. Mutations in recQ genes are linked to genome instability and human disease. To define the physical basis of RecQ enzyme function, we have dete...

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Detalhes bibliográficos
Main Authors: Bernstein, Douglas A., Zittel, Morgan C., Keck, James L.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC204483/
https://ncbi.nlm.nih.gov/pubmed/14517231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg500
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