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The mechanisms of [URE3] prion elimination demonstrate that large aggregates of Ure2p are dead-end products

The yeast prion [URE3] is a self-propagating inactive form (the propagon) of the Ure2 protein. Ure2p is composed of two domains: residues 1–93—the prion-forming domain (PFD)—and the remaining C-terminal part of the protein, which forms the functional domain involved in nitrogen catabolite repression...

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Publicat a:EMBO J
Autors principals: Ripaud, Leslie, Maillet, Laurent, Cullin, Christophe
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2003
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC204471/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14517262/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg488
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