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Desensitization of prostacyclin receptors in a neuronal hybrid cell line.

1 Prostacyclin and its stable analogue, carbacyclin, bind competitively to a single population of receptors, and activate adenylate cyclase of the NCB-20 neuronal somatic cell hybrid (Kact = 40.1 nM and 96.1 nM respectively). 2 Culture of NCB-20 cells in the presence of 1 microM carbacyclin for 4 to...

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Autores principales: Blair, I. A., Leigh, P. J., MacDermot, J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 1982
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2044635/
https://ncbi.nlm.nih.gov/pubmed/6289953
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