Interleukin 18 Participates in the Early Inflammatory Response and Bacterial Clearance during Pneumonia Caused by Nontypeable Haemophilus influenzae

Nontypeable Haemophilus influenzae (NTHi) is a common gram-negative respiratory pathogen. To determine the role of the proinflammatory cytokine interleukin 18 (IL-18) during NTHi pneumonia, normal wild-type (WT) and IL-18 knockout (KO) mice were intranasally infected with NTHi. IL-18 KO mice display...

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Detalhes bibliográficos
Main Authors: Wieland, Catharina W., Florquin, Sandrine, van der Poll, Tom
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Host Response and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2044539/
https://ncbi.nlm.nih.gov/pubmed/17664259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00287-07
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