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Studies on some para-substituted clonidine derivatives that exhibit an alpha-adrenoceptor stimulant activity.

1 alpha-Adrenoceptor stimulant activity was determined for noradrenaline (NA), clonidine and a series of para-substituted derivatives of clonidine on rat aortic strips, a rat brain synaptosome preparation, and anaesthetized pithed rats. The effects on the blood pressure of intraventricular (i.c.v.)...

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Main Authors: Leclerc, G., Rouot, B., Schwartz, J., Velly, J., Wermuth, C. G.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 1980
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2044396/
https://ncbi.nlm.nih.gov/pubmed/6110455
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