A potent new beta2-adrenoceptor blocking agent.

1 (t-Butyl-amino-3-ol-2-propyl) oximino-9 fluorene is a new beta2-adrenoceptor blocking agent with a pA2 of 9.23+/-0.25 on isolated trachea. 2 It provokes hypertension in normotensive rats and does not prevent arterial hypertension in SHR rats, although it does prevent the renin secretion normally i...

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Bibliographic Details
Main Authors: Imbs, J L, Miesch, F, Schwartz, J, Velly, J, Leclerc, G, Mann, A, Wermuth, C G
Format: Artigo
Language:Inglês
Published: 1977
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1667284/
https://ncbi.nlm.nih.gov/pubmed/19116
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