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Histamine H1-receptors in the brain of the guinea-pig and the rat: differences in ligand binding properties and regional distribution

1 The equilibrium dissociation constant, K(d), for mepyramine binding to a particulate fraction from rat brain, 9.1 nM, determined from inhibition of the binding of 1 nM [(3)H]-mepyramine, was distinctly higher than that, 0.83 nM, measured on an equivalent preparation from guinea-pig brain. 2 In rat...

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Detalhes bibliográficos
Main Authors: Hill, S.J., Young, J.M.
Formato: Artigo
Idioma:Inglês
Publicado em: 1980
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2044245/
https://ncbi.nlm.nih.gov/pubmed/7378642
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