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Effects of sulphasalazine and its metabolites on prostaglandin synthesis, inactivation and actions on smooth muscle

1 We have investigated the effects of sulphasalazine and of its principal colonic metabolites (5-aminosalicylic acid and sulphapyridine) on prostaglandin inactivation, synthesis and actions on gastrointestinal smooth muscle. 2 Sulphasalazine inhibits prostaglandin F(2α) breakdown in 100,000 g supern...

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Main Authors: Hoult, J.R.S., Moore, P.K.
Formato: Artigo
Idioma:Inglês
Publicado: 1980
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2044233/
https://ncbi.nlm.nih.gov/pubmed/6103724
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