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Sulphasalazine is a potent inhibitor of prostaglandin 15-hydroxydehydrogenase: possible basis for therapeutic action in ulcerative colitis.

Sulphasalazine is a potent and selective inhibitor in vitro of prostaglandin 15-hydroxydehydrogenase in rabbit colon (ID50 = 50 micrometer) and in several other organs of different species, but does not inhibit prostaglandin delta-13 reductase or microsomal prostaglandin synthesis from arachidonic a...

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Bibliografiska uppgifter
Huvudupphovsmän: Hoult, J R, Moore, P K
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1978
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1668267/
https://ncbi.nlm.nih.gov/pubmed/29685
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