Natural killer-like nonspecific tumor cell lysis mediated by specific ligand-activated Vα14 NKT cells

We have recently identified α-galactosylceramide (α-GalCer) as a specific ligand for an invariant Vα14/Vβ8.2 T cell receptor exclusively expressed on the majority of Vα14 NKT cells, a novel subset of lymphocytes. Here, we report that α-GalCer selectively activates Vα14 NKT cells resulting in prevent...

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Autors principals: Kawano, Tetsu, Cui, Junqing, Koezuka, Yasuhiko, Toura, Isao, Kaneko, Yoshikatsu, Sato, Hiroshi, Kondo, Eisuke, Harada, Michishige, Koseki, Haruhiko, Nakayama, Toshinori, Tanaka, Yujiro, Taniguchi, Masaru
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 1998
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC20440/
https://ncbi.nlm.nih.gov/pubmed/9576945
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