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Analysis of anomalous pKB values for metiamide and atropine in the isolated stomach of the mouse

1 In the isolated, lumen-perfused, stomach preparation of the mouse, metiamide was found by kinetic analysis to behave like a simple competitive antagonist of histamine-stimulated acid secretion. However, the pK(B) estimate of 5.08 was significantly lower than that found in guinea-pig atrium (6.0) o...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Angus, J.A., Black, J.W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1979
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2043596/
https://ncbi.nlm.nih.gov/pubmed/497522
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