Multiple Immunizations with Adenovirus and MVA vectors improve CD8(+) T cell functionality and mucosal homing

Recombinant adenovirus vectors and MVA vectors were used in prime boost vaccine regimens to address the impact of repeated immunizations on transgene product-specific CD8(+) T cell frequencies, phenotypes, function, and localization. We show that a regimen with three immunizations incorporating MVA,...

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Huvudupphovsmän: Tatsis, Nia, Lin, Shih-Wen, Harris-McCoy, Kimberly, Garber, David A., Feinberg, Mark B., Ertl, Hildegund C.J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2007
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2043483/
https://ncbi.nlm.nih.gov/pubmed/17590405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2007.05.028
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