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Yersinia pestis CO92ΔyopH Is a Potent Live, Attenuated Plague Vaccine
An in-frame deletion of the yopH gene in Yersinia pestis CO92 attenuates virulence in both bubonic and pneumonic plague models. When it is used as a live, attenuated vaccine, CO92ΔyopH provides a high degree of protection from parental and respiratory challenge with Y. pestis CO92.
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| Asıl Yazarlar: | , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Microbiology (ASM)
2007
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2043315/ https://ncbi.nlm.nih.gov/pubmed/17652523 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00137-07 |
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