Association of Saquinavir Plasma Concentrations with Side Effects but Not with Antiretroviral Outcome in Patients Infected with Protease Inhibitor-Susceptible Human Immunodeficiency Virus Type 1

The objective of this study was to identify parameters among saquinavir pharmacokinetics, patients' demographics or comedications, to be addressed for improved personalized therapy. The presence of human immunodeficiency virus type 1 (HIV-1) RNA at therapy week 48 (principal target parameter),...

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Main Authors: Lötsch, Jörn, Harder, Sebastian, Stürmer, Martin, Doerr, Hans-Wilhelm, Geisslinger, Gerd, Staszewski, Schlomo, von Hentig, Nils
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2007
Assuntos:
Clinical Therapeutics
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2043227/
https://ncbi.nlm.nih.gov/pubmed/17576836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00036-07
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