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In Vitro and In Vivo Activities of T-705 against Arenavirus and Bunyavirus Infections

There is a need for the development of effective antivirals for the treatment of severe viral diseases caused by members of the virus families Bunyaviridae and Arenaviridae. The pyrazine derivative T-705 (6-fluoro-3-hydroxy-2-pyrazinecarboxamide) has demonstrated remarkable antiviral activity agains...

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Autori principali: Gowen, Brian B., Wong, Min-Hui, Jung, Kie-Hoon, Sanders, Andrew B., Mendenhall, Michelle, Bailey, Kevin W., Furuta, Yousuke, Sidwell, Robert W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2043187/
https://ncbi.nlm.nih.gov/pubmed/17606691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00356-07
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