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Structural Basis for Polypyrimidine-Tract Recognition by the Essential pre-mRNA Splicing Factor U2AF(65)
The essential pre-mRNA splicing factor, U2AF(65), guides the early stages of splice site choice by recognizing a polypyrimidine (Py)-tract consensus sequence near the 3′-splice site. Since Py-tracts are relatively poorly conserved in higher eukaryotes, U2AF(65) is faced with the problem of specifyin...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2006
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2043114/ https://ncbi.nlm.nih.gov/pubmed/16818232 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2006.05.025 |
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