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AN EVOLVING CELLULAR PATHOLOGY OCCURS IN DORSAL ROOT GANGLIA, PERIPHERAL NERVE AND SPINAL CORD FOLLOWING INTRAVENOUS ADMINISTRATION OF PACLITAXEL IN THE RAT
Paclitaxel (Taxol®) is a frontline antineoplastic agent used to treat a variety of solid tumors including breast, ovarian, or lung cancer. The major dose limiting side effect of paclitaxel is a peripheral sensory neuropathy that can last days to a lifetime. To begin to understand the cellular events...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2042964/ https://ncbi.nlm.nih.gov/pubmed/17698044 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2007.06.066 |
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