Protease-activated receptor-4: a novel mechanism of inflammatory pain modulation

BACKGROUND AND PURPOSE: Protease-activated receptor-4 (PAR(4)), the most recently discovered member of the PARs family, is activated by thrombin, trypsin and cathepsin G, but can also be selectively activated by small synthetic peptides (PAR(4)-activating peptide, PAR(4)-AP). PAR(4) is considered a...

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Bibliographic Details
Main Authors: Asfaha, S, Cenac, N, Houle, S, Altier, C, Papez, M D, Nguyen, C, Steinhoff, M, Chapman, K, Zamponi, G W, Vergnolle, N
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2006
Subjects:
Research Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2042908/
https://ncbi.nlm.nih.gov/pubmed/17179954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706975
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