Pharmacokinetics of temocapril and temocaprilat after 14 once daily oral doses of temocapril in hypertensive patients with varying degrees of renal impairment

Aims The aim of this study was to determine the potential influence of renal impairment on the pharmacokinetics of temocapril and its pharmacologically active diacid metabolite, temocaprilat. Methods Non-compartmental pharmacokinetics were assessed in four groups of hypertensive patients (n=8 per gr...

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Bibliografski detalji
Glavni autori: Püchler, K., Eckl, K. M., Fritsche, L., Renneisen, K., Neumayer, H.-H., Sierakowski, B., Lavrijssen, A. T. J., Thomsen, T., Roots, I.
Format: Artigo
Jezik:Inglês
Izdano: 1997
Teme:
Original Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2042893/
https://ncbi.nlm.nih.gov/pubmed/9431827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1997.t01-1-00622.x
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