Pharmacokinetics of temocapril and temocaprilat after 14 once daily oral doses of temocapril in hypertensive patients with varying degrees of renal impairment

Aims The aim of this study was to determine the potential influence of renal impairment on the pharmacokinetics of temocapril and its pharmacologically active diacid metabolite, temocaprilat. Methods Non-compartmental pharmacokinetics were assessed in four groups of hypertensive patients (n=8 per gr...

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Main Authors: Püchler, K., Eckl, K. M., Fritsche, L., Renneisen, K., Neumayer, H.-H., Sierakowski, B., Lavrijssen, A. T. J., Thomsen, T., Roots, I.
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2042893/
https://ncbi.nlm.nih.gov/pubmed/9431827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1997.t01-1-00622.x
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