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Pharmacokinetics of digoxin-specific Fab: effects of decreased renal function and age

Aims To study the influence of age and renal function on digoxin-specific Fab (DS-Fab) pharmacokinetics. Methods Sixteen patients (35–91 years) with creatinine clearance ranging from 10.6 to 122.1 ml min(−1) who had been admitted to hospital with severe digoxin or digitoxin self-poisoning were treat...

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Autori principali: Renard, C., Grene-Lerouge, N., Beau, N., Baud, F., Scherrmann, J. M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1997
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2042825/
https://ncbi.nlm.nih.gov/pubmed/9278197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1997.00654.x
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