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Concentrations and effects of zopiclone are greatly reduced by rifampicin

Aims The effects of rifampicin on the pharmacokinetics and pharmacodynamics of zopiclone, a non-benzodiazepine hypnotic, were studied. Methods In a randomized, placebo-controlled cross-over study with two phases, eight young healthy volunteers took either 600 mg rifampicin or placebo once daily for...

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Bibliografiset tiedot
Päätekijät: Villikka, K., Kivistö, K. T., Lamberg, T. S., Kantola, T., Neuvonen, P. J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1997
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2042775/
https://ncbi.nlm.nih.gov/pubmed/9159561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1997.00579.x
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