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Concentrations and effects of buspirone are considerably reduced by rifampicin

AIMS: The effects of rifampicin on the pharmacokinetics and pharmacodynamics of buspirone, a non-benzodiazepine anxiolytic agent, were investigated. METHODS: In a randomized, placebo-controlled cross-over study with two phases, 10 young healthy volunteers took either 600 mg rifampicin or matched pla...

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Detalhes bibliográficos
Main Authors: Lamberg, T S, Kivistö, K T, Neuvonen, P J
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1873961/
https://ncbi.nlm.nih.gov/pubmed/9578186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1998.t01-1-00698.x
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