Enhanced effect of triazolam with diltiazem

Aims Triazolam, a triazolobenzodiazepine hypnotic agent, is metabolized by CYP3A4. Diltiazem is an inhibitor of this isozyme. The aim of this study was to determine if diltiazem affects plasma concentrations of triazolam in humans. Methods We investigated the interaction between triazolam and diltia...

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Detaylı Bibliyografya
Asıl Yazarlar: Kosuge, Kazuhiro, Nishimoto, Masahiko, Kimura, Masahiko, Umemura, Kazuo, Nakashima, Mitsuyoshi, Ohashi, Kyoichi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Blackwell Science Inc 1997
Konular:
Original Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2042761/
https://ncbi.nlm.nih.gov/pubmed/9146848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1997.00580.x
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