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Attenuation by ACE inhibitor drugs of α-adrenoceptor sensitivity in human vessels: possible differences related to drug lipophilicity

AIMS: We investigated the effect of angiotensin converting enzyme inhibitors (ACEIs) on postsynaptic adrenoceptor sensitivity and compared the effect of the lipophilic ACEI, quinapril, and that of hydrophilic agent, enalapril in human vessels. METHODS: α-adrenoceptor sensitivity was evaluated using...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kimura, Masahiko, Umemura, Kazuo, Kosuge, Kazuhiro, Nishimoto, Masahiko, Ohashi, Kyoichi, Nakashima, Mitsuyoshi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Science Inc 1998
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1873805/
https://ncbi.nlm.nih.gov/pubmed/9862250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1998.00834.x
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