Attenuation by ACE inhibitor drugs of α-adrenoceptor sensitivity in human vessels: possible differences related to drug lipophilicity

AIMS: We investigated the effect of angiotensin converting enzyme inhibitors (ACEIs) on postsynaptic adrenoceptor sensitivity and compared the effect of the lipophilic ACEI, quinapril, and that of hydrophilic agent, enalapril in human vessels. METHODS: α-adrenoceptor sensitivity was evaluated using...

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Bibliografische gegevens
Hoofdauteurs: Kimura, Masahiko, Umemura, Kazuo, Kosuge, Kazuhiro, Nishimoto, Masahiko, Ohashi, Kyoichi, Nakashima, Mitsuyoshi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Blackwell Science Inc 1998
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Original Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1873805/
https://ncbi.nlm.nih.gov/pubmed/9862250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1998.00834.x
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