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Evidence for both in vivo and in vitro interaction between vigabatrin and alanine transaminase
Aims Decreases in plasma alanine transaminase (ALA-T) activity of 20–100% have been reported following the use of vigabatrin (Sabril) in patients with uncontrolled epilepsy. This effect has a potential clinical significance as it may mask signs of early, underlying hepatic disease. It is particularl...
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Main Authors: | , , , |
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Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
1997
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2042723/ https://ncbi.nlm.nih.gov/pubmed/9131948 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1997.05295.x |
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