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Evidence for both in vivo and in vitro interaction between vigabatrin and alanine transaminase

Aims Decreases in plasma alanine transaminase (ALA-T) activity of 20–100% have been reported following the use of vigabatrin (Sabril) in patients with uncontrolled epilepsy. This effect has a potential clinical significance as it may mask signs of early, underlying hepatic disease. It is particularl...

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Detalhes bibliográficos
Main Authors: Richens, Alan, McEwan, Jean R., Deybach, Jean C., Mumford, John P.
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2042723/
https://ncbi.nlm.nih.gov/pubmed/9131948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1997.05295.x
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