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Proguanil metabolism in relation to S-mephenytoin oxidation in a Turkish population

The oxidation of proguanil was studied in 89 unrelated healthy Turkish volunteers after administration of proguanil (single dose, 200 mg, orally). Based on the distribution of the ratio of proguanil to cycloguanil excreted in urine, and using an antimode value of 15, the prevalence of poor metaboliz...

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Hlavní autoři: BASCI, N. E., BOZKURT, A., KORTUNAY, S., ISIMER, A., SAYAL, A., KAYAALP, S. O.
Médium: Artigo
Jazyk:Inglês
Vydáno: 1996
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2042714/
https://ncbi.nlm.nih.gov/pubmed/8971434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1996.00500.x
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