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Pharmacodynamics of oxypurinol after administration of allopurinol to healthy subjects
1 Eight healthy subjects received 50, 100, 300, 600 and 900 mg allopurinol daily for 1 week each, in random order with 1 week separating each treatment period. The pre-dose plasma concentration of oxypurinol, the extent of inhibition of xanthine oxidase, plasma urate concentration and urine urate ex...
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| Main Authors: | , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
1996
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2042594/ https://ncbi.nlm.nih.gov/pubmed/8730975 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1996.03116.x |
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