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Activin A is a critical component of the inflammatory response, and its binding protein, follistatin, reduces mortality in endotoxemia
Activin A is a member of the transforming growth factor-β superfamily, which we have identified as having a role in inflammatory responses. We show that circulating levels of activin increase rapidly after LPS-induced challenge through activation of Toll-like receptor 4 and the key adaptor protein,...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2007
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2042191/ https://ncbi.nlm.nih.gov/pubmed/17911255 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0705971104 |
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