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Metabolic Engineering of Saccharomyces cerevisiae for Conversion of d-Glucose to Xylitol and Other Five-Carbon Sugars and Sugar Alcohols

Recombinant Saccharomyces cerevisiae strains that produce the sugar alcohols xylitol and ribitol and the pentose sugar d-ribose from d-glucose in a single fermentation step are described. A transketolase-deficient S. cerevisiae strain accumulated d-xylulose 5-phosphate intracellularly and released r...

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Bibliographic Details
Main Authors: Toivari, Mervi H., Ruohonen, Laura, Miasnikov, Andrei N., Richard, Peter, Penttilä, Merja
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2007
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2042063/
https://ncbi.nlm.nih.gov/pubmed/17630301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.02707-06
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