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Optimizing the protein switch: altering nuclear import and export signals, and ligand binding domain
Ligand regulated localization controllable protein constructs were optimized in this study. Several constructs were made from a classical nuclear export signal (HIV-rev, MAPKK, or progesterone receptor) in combination with a SV40 T-antigen type nuclear import signal. Different ligand binding domains...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2007
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2041942/ https://ncbi.nlm.nih.gov/pubmed/17574289 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2007.04.017 |
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