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A Non-uniform Stepping Mechanism for E. coli UvrD Monomer Translocation along Single Stranded DNA

E. coli UvrD is an SF1 helicase involved in several DNA metabolic processes. Although a UvrD dimer is needed for helicase activity, a monomer can translocate with 3′ to 5′ directionality along single stranded DNA and this ATP-dependent translocation is likely involved in RecA displacement. In order...

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Bibliografiske detaljer
Main Authors: Tomko, Eric J., Fischer, Christopher J., Niedziela-Majka, Anita, Lohman, Timothy M.
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2041850/
https://ncbi.nlm.nih.gov/pubmed/17499041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2007.03.024
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