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Alzheimer’s-specific effects of soluble β-amyloid on protein kinase C-α and -γ degradation in human fibroblasts
Alzheimer’s disease (AD) is a multifactorial disease in which β-amyloid peptide (βAP) plays a critical role. We report here that the soluble fraction 1–40 of βAP differentially degrades protein kinase C-α and -γ (PKCα and PKCγ) isoenzymes in normal (age-matched controls, AC) and AD fibroblasts most...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1998
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC20417/ https://ncbi.nlm.nih.gov/pubmed/9576922 |
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