Mercuric chloride-induced renal tubular necrosis in the rat.

A light microscopic study of the renal tubulonecrotic lesion in rats given a small dose of HgCl2 is described. The changes consist of a rapidly developing vacuolation of the cytoplasm with loss of basophilic staining within 4 h that leads to cell breakdown, fragmentation and dissolution by 48 h. Nuc...

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Bibliographic Details
Main Authors: Haagsma, B. H., Pound, A. W.
Format: Artigo
Language:Inglês
Published: 1979
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2041474/
https://ncbi.nlm.nih.gov/pubmed/508584
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