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Kinetics and pathogenicity of autoantibodies induced by mercuric chloride in the brown Norway rat.

Repeated low-dose injections of mercuric chloride (HgCl2) in the brown Norway (BN) rat result in polyclonal activation which includes the induction of anti-glomerular basement membrane (GBM) autoantibodies. We examined the kinetics of various autoantibodies produced in vivo, general features of poly...

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Detalhes bibliográficos
Main Authors: Pusey, C D, Bowman, C, Morgan, A, Weetman, A P, Hartley, B, Lockwood, C M
Formato: Artigo
Idioma:Inglês
Publicado em: 1990
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1535003/
https://ncbi.nlm.nih.gov/pubmed/2199099
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