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A Novel, Topologically Constrained DNA Molecule Containing a Double Holliday Junction: DESIGN, SYNTHESIS, AND INITIAL BIOCHEMICAL CHARACTERIZATION

The double Holliday junction (dHJ) is a central intermediate to homologous recombination, but biochemical analysis of the metabolism of this structure has been hindered by the lack of a substrate that adequately replicates the endogenous structure. We have synthesized a novel dHJ substrate that cons...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Plank, Jody L., Hsieh, Tao-shih
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2041448/
https://ncbi.nlm.nih.gov/pubmed/16608853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M602933200
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