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A Novel, Topologically Constrained DNA Molecule Containing a Double Holliday Junction: DESIGN, SYNTHESIS, AND INITIAL BIOCHEMICAL CHARACTERIZATION
The double Holliday junction (dHJ) is a central intermediate to homologous recombination, but biochemical analysis of the metabolism of this structure has been hindered by the lack of a substrate that adequately replicates the endogenous structure. We have synthesized a novel dHJ substrate that cons...
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Hauptverfasser: | , |
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Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
2006
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Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2041448/ https://ncbi.nlm.nih.gov/pubmed/16608853 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M602933200 |
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