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A Novel, Topologically Constrained DNA Molecule Containing a Double Holliday Junction: DESIGN, SYNTHESIS, AND INITIAL BIOCHEMICAL CHARACTERIZATION

The double Holliday junction (dHJ) is a central intermediate to homologous recombination, but biochemical analysis of the metabolism of this structure has been hindered by the lack of a substrate that adequately replicates the endogenous structure. We have synthesized a novel dHJ substrate that cons...

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Detalhes bibliográficos
Main Authors: Plank, Jody L., Hsieh, Tao-shih
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2041448/
https://ncbi.nlm.nih.gov/pubmed/16608853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M602933200
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