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Induction of Cullin 7 by DNA damage attenuates p53 function
The p53 tumor suppressor gene encodes a transcription factor, which is translationally and posttranslationally activated after DNA damage. In a proteomic screen for p53 interactors, we found that the cullin protein Cul7 efficiently associates with p53. After DNA damage, the level of Cul7 protein inc...
Tallennettuna:
| Päätekijät: | , , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
National Academy of Sciences
2007
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2040908/ https://ncbi.nlm.nih.gov/pubmed/17586686 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0609467104 |
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