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Deletion of 14-3-3σ sensitizes mice to DMBA/TPA-induced papillomatosis

The p53-inducible cell cycle regulator 14-3-3σ exhibits tumor suppressive functions and is highly expressed in differentiating layers of the epidermis and hair follicles. 14-3-3σ/SFN/stratifin is frequently silenced in human epithelial cancers, and experimental down-regulation of 14-3-3σ expression...

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Pubblicato in:Oncotarget
Autori principali: Winter, Markus, Lodygin, Dmitri, Verdoodt, Berlinda, Hermeking, Heiko
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5216908/
https://ncbi.nlm.nih.gov/pubmed/27409835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10478
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