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Analysis of concentration-dependent functions of PU.1 in hematopoiesis using mouse models

The Ets family transcription factor PU.1, encoded by the gene Sfpi1, is essential for normal hematopoiesis. A number of studies have suggested that changes in PU.1 concentration play a role in directing cell fate decisions during hematopoiesis. However, the stages of hematopoietic development at whi...

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Bibliographic Details
Main Authors: DeKoter, Rodney P., Kamath, Meghana B., Houston, Isaac B.
Format: Artigo
Language:Inglês
Published: 2007
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2040501/
https://ncbi.nlm.nih.gov/pubmed/17629523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcmd.2007.06.004
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